The association of arterial shear and flow-mediated dilation in diabetes
نویسندگان
چکیده
منابع مشابه
Shear stress and flow-mediated dilation.
In this edition of Hypertension, the Framingham Heart Study group reports on the relationship between diastolic shear stress and brachial artery flow mediated dilation (FMD) in 2045 participants of the Framingham Offspring group.1 Clinical correlates and heritability of FMD in the participants have been published previously.2 The new report1 challenges conventional concepts on endothelial funct...
متن کاملAssociation of Flow-mediated Dilation with Shear Rate in Patients and Healthy Volunteers
Introduction: Flow mediated-dilation (FMD) is a noninvasive test of endothelial function based on shear stressdependent nitric oxide secretion causing vasodilation. Normalization of FMD to shear stress was previously proposed. The aim of present study is an examination of relationship between shear rate and FMD in patients with hypertension and atherosclerosis in comparison with healthy volunte...
متن کاملSympathetic nervous system activation, arterial shear rate, and flow-mediated dilation.
The aim of this study was to examine the contribution of arterial shear to changes in flow-mediated dilation (FMD) during sympathetic nervous system (SNS) activation in healthy humans. Ten healthy men reported to our laboratory four times. Bilateral FMD, shear rate (SR), and catecholamines were examined before/after 10-min of -35-mmHg lower body negative pressure (LBNP10). On day 1, localized f...
متن کاملPotentially spurious correlations between arterial size, flow-mediated dilation, and shear rate.
The use of indices formed from the ratio of 2 variables often generates spurious correlations with other variables that are mathematically coupled. In this context, we examined the correlations between percent flow-mediated dilation, baseline diameter, and shear rate. In a sample of 315 participants, with and without substantial vascular risk factors, the observed correlation coefficients betwe...
متن کاملLocal Shear Stress and Brachial Artery Flow–Mediated Dilation
Endothelium-dependent flow-mediated dilation is a homeostatic response to short-term increases in local shear stress. Flow-mediated dilation of the brachial artery in response to postischemic reactive hyperemia is impaired in patients with cardiovascular disease risk factors and may reflect local endothelial dysfunction in the brachial artery. However, previous studies have largely neglected th...
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ژورنال
عنوان ژورنال: Vascular Medicine
سال: 2011
ISSN: 1358-863X,1477-0377
DOI: 10.1177/1358863x11411361